"ENGLAND HATH SEENE HER BEST DAYES, AND NOW EVILL DAYES ARE BEFALLING US." NOSTALGIA IN PURITAN CULTURE


Suppression of Ribosome Biogenesis by Targeting WD Repeat Domain 12 (WDR12) Inhibits Glioma Stem-Like Cell Growth

Glioma stem-like cells (GSCs) are a subset of tumor cells that initiate malignant growth and promote the therapeutic resistance of glioblastoma, the most lethal primary Bronzer brain tumor.Ribosome biogenesis is an essential cellular process to maintain cell growth, but its regulatory mechanism in GSCs remains largely unknown.Here, we show that WD

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Genetic engineering of cotton with a novel cry2AX1 gene to impart insect resistance against Helicoverpa armigera

Embryogenic calli of cotton (Coker310) were cocultivated with the Agrobacterium tumefaciens strain LBA4404 harbouring the codon-optimised, chimeric cry2AX1 gene consisting of sequences from cry2Aa and cry2Ac genes isolated from Indian strains Moleskin Caps of Bacillus thuringiensis.Forty-eight putative transgenic plants were regenerated, and PCR an

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